| HISTORY | EXAMINATION | INVESTIGATION | FOCI |
| Dysuria, Frequency, Nocturia Flank pain Recent bladder instrumentation/IDC |
Suprapubic/Flank tenderness | Urinalysis - leucocytes, nitrates, blood MSU |
UTI |
| Cough/Sputum Dyspnea Chest pain |
Tachypnea Decreased oxygenation Focal chest findings |
CXR abnormalities | LRTI |
| Headache Photophobia Recent respiratory infection |
Neck stiffness Altered concious state Seizures (esp. encephalitis) Focal signs (if abscess) |
CT brain Lumbar puncture |
CNS infections |
| Positional headache Facial pain Purulent rhinorrhea Post-nasal drip Maxillary dental pain |
Sinus tenderness | Sinus xrays | Sinusitis |
| Otalgia Ear discharge |
Red, bulging drum | Otitis media | |
| Non-specific GI symptoms Nausea, vomiting, diarrhea or constipation Dysuria (adherent inflammatory mass to bladder) |
Localised abdominal tenderness with peritonism | Abdominal U/S Abdominal CT |
Intrabdominal infection |
| Perianal pain, swelling or discharge | Rectal tenderness | Rectal swab | Perianal infection |
| Pelvic pain PV discharge Dyspareunia Tampon use Recent gynae instrumentation STD risk factors |
Cervical excitation Adnexal tenderness/mass |
Vaginal swab | Gynaecological infection |
| Open sores/rashes Recent skin trauma/surgical trauma |
Skin inflammation | Cellulitis | |
| Bone/Joint pain | Bone tenderness Decreased ROM Joint swelling/tenderness |
Joint aspirate | Osteomyelitis Septic arthritis Septic bursitis |